According to the Global Pharmaceutical Excipients Procurement Market Intelligence Report, “suppliers are adopting new technologies, such as nanotechnology for enhancing the capabilities of excipients.” As a result, the driving factors of this growth and focus is due to the research and development of the use for these in therapeutics and biosimilars. As the trend continues to expand with biological actives, macromolecules and discovery of novel APIs, there is an increased need and further understanding of existing excipients, as well as development of new excipients.
The growth of the biologics and biosimilar markets are obviously fueling this demand. As mentioned in our 7 Things to Know About Biosimilars Drugs Post, this fast-growing segment is making significant strides in the industry as it enters new markets. Since the demand for customization in biosimilars is so high, it is increasing the demand for new technologies and processes. This has, as a result, introduced a number of modifications to existing monographed excipients. As this progression within the biosimilars market continues, there will be a direct correlation to the increase demand for new applications for excipients, both existing ones as well as newly developed excipients.
The role of excipients are key to drug production. These raw materials help with solubility, stability and shelf-life. While it is expected the current monographed excipients will not be sufficient to satisfy the newly discovered actives in the future, the functional roles of excipients remains clear. Excipients play a valuable role in drug delivery as fillers, wetting agents, emulsifiers, preservatives, flavorants, colorants, absorption enhancers, sustained-release matrices, and diluents. While not the active pharmaceutical ingredient, per se, these valuable products allow the API to perform, as prescribed, with precision in the consistent management of the patients illness.